
Hope Beyond Medication
For individuals battling depression, OCD, PTSD, or chronic pain, standard medications don’t always work. At TMS of Palm Beach in Boca Raton, we offer advanced ketamine-based therapies, including FDA-approved Spravato® (esketamine) nasal spray and IV ketamine infusions, to provide rapid relief when other treatments have failed.
These therapies target the brain in new ways, offering hope to those struggling with treatment-resistant conditions—and helping patients reclaim their quality of life.
What Is Spravato®?
Spravato® is an FDA-approved form of esketamine delivered as a nasal spray under the supervision of a healthcare professional. It is specifically indicated for adults with treatment-resistant depression and is used alongside an SSRI or SNRI.
By targeting NMDA receptors in the brain, Spravato® works differently from traditional antidepressants, restoring balance in brain activity and relieving symptoms more effectively.
In clinical studies of over 1,800 patients, Spravato® combined with antidepressants showed higher success rates than antidepressants alone. Many patients report relief within hours to days—far faster than typical oral medications.
IV Ketamine Infusion Therapy
For patients who may not qualify for Spravato®, or who benefit from a different approach, we also provide IV ketamine infusions.
Administered in precise, sub-anesthetic doses over 60 minutes, IV ketamine has been shown to reduce symptoms of:
Treatment-Resistant Depression
Major Depression with suicidal ideation
Bipolar Depression
PTSD and Anxiety Disorders
OCD
Fibromyalgia and Chronic Pain
Most patients describe the experience as calming—often a sense of “floating” or deep relaxation. After treatment, patients are monitored until they are fully alert, and many report rapid improvement in mood and outlook.
Conditions We Treat with Ketamine-Based Therapy

Treatment-Resistant Depression (TRD)

PTSD (Post-Traumatic Stress Disorder)
Why Choose Ketamine Therapy?
Unlike traditional antidepressants, which can take weeks or months to take effect, ketamine therapies often provide relief within hours or days. This speed can be life-saving for individuals in severe distress.
Ketamine and Spravato® also work for patients labeled as “treatment-resistant,” offering a scientifically backed alternative when standard medications fail. Studies confirm significant improvements in both mood regulation and pain symptoms, helping patients regain stability and hope for the future.
FAQs About Ketamine Therapy & Spravato®

Discover a Faster Path to Relief
If you’ve tried medications without success, it may be time to explore ketamine-based therapy. Spravato® and IV ketamine treatments at TMS of Palm Beach offer safe, effective, and often life-changing options for treatment-resistant depression and related conditions.